Table 2.
Results of Genetic Association in the Replication Cohort of 246 Case Subjects and 1,685 Unrelated Control Subjects for 7 SNPs in Loci Observed in the Discovery GWAS
| Locus | SNP | Minor Allele | p Value | OR | 95% CI |
|---|---|---|---|---|---|
| 1p36 (GRHL3) | rs41268753 | T | 2.81 × 10−4 | 2.16 | 1.43–3.27 |
| rs113965554 | A | 6.82 × 10−4 | 1.97 | 1.33–2.91 | |
| 6p26 (PARK2) | rs12175475 | T | 0.97 | 0.99 | 0.52–1.87 |
| rs9347594 | T | 0.97 | 1.00 | 0.82–1.21 | |
| rs9365380 | T | 0.91 | 1.01 | 0.83–1.23 | |
| 11q22.1 (YAP1) | rs11225351 | T | 0.81 | 1.03 | 0.83–1.28 |
| rs117496742 | A | 0.20 | 0.60 | 0.27–1.31 |