Table S2.

BrdU incorporation in notochord lineage in T-shRNA;RosaLacZ;ShhCre and control sibling RosaLacZ;ShhCre embryos

Sections analyzed	No. of BrdU+ cells	Total cell no.	BrdU+ fraction	Average BrdU+ fraction	Age-average BrdU+ fraction	SD*
E10.5 T-shRNA(−);ShhCre (control)
Litter 1
Section 1	1	9	0.11	0.18	0.15	0.02
Section 2	1	7	0.14
Section 3	3	11	0.27
Litter 2
Section 1	2	12	0.17	0.14
Section 2	1	10	0.10
Section 3	2	13	0.15
Litter 3
Section 1	2	11	0.18	0.14
Section 2	1	12	0.08
Section 3	1	6	0.17
E10.5 T-shRNA(+);ShhCre
Litter 1
Section 1	9	24	0.38	0.35	0.34	0.01
Section 2	11	30	0.37
Section 3	11	37	0.30
Litter 2
Section 1	10	34	0.29	0.34
Section 2	5	14	0.36
Section 3	11	29	0.38
Litter 3
Section 1	7	21	0.33	0.33
Section 2	10	34	0.29
Section 3	13	37	0.35
E11.5 T-shRNA(−);ShhCre (control)
Litter 1
Section 1	1	9	0.11	0.13	0.16	0.03
Section 2	2	10	0.20
Section 3	1	13	0.08
Litter 2
Section 1	4	16	0.25	0.19
Section 2	2	16	0.13
Litter 3
Section 1	2	13	0.15	0.15
Section 2	2	14	0.14
Section 3	2	13	0.15
E11.5 T-shRNA(+);ShhCre
Litter 1
Section 1	17	50	0.34	0.46	0.43	0.04
Section 2	40	76	0.53
Section 3	29	55	0.53
Litter 2
Section 1	33	76	0.43	0.39
Section 2	20	67	0.30
Section 3	29	70	0.41
Section 4	34	86	0.40
Section 5	33	82	0.40
Litter 3
Section 1	12	28	0.43	0.42
Section 2	34	80	0.43
Section 3	15	40	0.38
Section 4	28	60	0.47

^*Standard deviation.