Fig. S6.

Dissociated cells NPE and PE cells from Trpv4^−/− CBs. Compared with WT (e.g., Fig. 4), both AA- (100 μM) and 11′,12′-EET- (5 μM) induced ${\left[{\text{Ca}}^{2\mathrm{+}}\right]}_{\text{i}}$ responses are curtailed in KO NPE cells. A residual AA-sensitive increase (P < 0.05) in NPE cells suggests a possible, auxiliary AA-sensitive Ca²⁺ pathway (46).