. 2016 Apr 15;11(4):e0153694. doi: 10.1371/journal.pone.0153694

Table 2. Blood Pressure of Mice.

Group	SBP (mmHg)	DBP (mmHg)	MAP (mmHg)
Control	122 ± 7^*	93 ± 7^*	101 ± 7^*
T4	144 ± 3	109 ± 3	120 ± 3
DMSO + T4	147 ± 4	116 ± 4	126 ± 4
Sorafenib + T4	149 ± 4	112 ± 5	124 ± 5
Tadalafil_IP + T4	144 ± 2	111 ± 2	122 ± 2
Tadalafil_Or + T4	132 ± 4	103 ± 4	112 ± 4
CMC + T4	151 ± 2	119 ± 3	130 ± 3
Macitentan_LD + T4	148 ± 4	116 ± 4	126 ± 4
Macitentan_HD + T4	149 ± 2	121 ± 2	130 ± 2

SBP: systolic blood pressure, DBP: diastolic blood pressure, MAP: mean arterial pressure, Control; n = 11, Thyroxin (T4); n = 22, Dimethyl sulfoxide (DMSO); N = 6, Sorafenib; n = 13, Tadalafil_IP (intraperitoneal, 1 mg/kg); n = 7, Tadalafil_Or (oral, 4 mg/kg); n = 8, carboxymethylcellulose (CMC); n = 10, Macitentan_LD (Low dose: 30 mg/kg); n = 10, Macitentan_HD (High dose: 100 mg/kg); n = 8.

*: indicates a significant change as revealed by one-way ANOVA followed by Dunnett Multiple Comparisons post-hoc test, comparing all groups to T4.