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. 2016 Apr 15;11(4):e0153828. doi: 10.1371/journal.pone.0153828

Table 3. Risk for offspring chronic musculoskeletal pain associated with the combined effect of parental chronic musculoskeletal pain and offspring leisure time physical activity.

Offspring activity-interfering CMP
Variables High leisure time physical activity Moderate leisure time physical activity Low leisure time physical activity
No CMP
Cases/non-cases 49/301 38/239 48/188
Age-adjusted RR 1.00 0.96 1.40
RRa 1.00 (Ref.) 0.91 (0.62, 1.36) 1.29 (0.89, 1.87)
Any CMP, one parent
Case/non-case 215/894 241/780 202/659
Age-adjusted RR 1.36 1.61 1.56
RRa 1.30 (0.97, 1.75) 1.51 (1.13, 2.03) 1.38 (1.03, 1.87)
Any CMP, both parents
Case/non-case 86/352 82/307 96/217
Age-adjusted RR 1.39 1.45 2.12
RRa 1.32 (0.95, 1.84) 1.34 (0.96, 1.86) 1.82 (1.32, 2.50)

CMP: chronic musculoskeletal pain, CI: confidence interval, RR: relative risk.

aAdjusted for offspring factors in HUNT2; age (continuous), sex, body mass index (underweight, normal weight, overweight, obese, or unknown), physical work demands (mostly sedentary, much walking, much walking and lifting, heavy physical work, or unknown), psychological well-being (satisfied, somewhat satisfied, dissatisfied, or unknown), and education (<10 years, 10–12 years, ≥13 years, or unknown).