Table 3.
SVR rates of 50 HCV-infected Patients Treated On-site with Triple Therapy at Opiate Agonist Treatment Program
| Characteristic | N (%) or Mean (± SD) | SVR (n=50) | OR (95% CI) for SVR |
|---|---|---|---|
|
| |||
| Recent drug use | |||
| Used within 6 months | 26 (52) | 15/26 (58) | Ref |
| Used more than 6 months ago | 24 (58) | 16/24 (67) | 1.47 (0.46 , 4.64) |
|
| |||
| Active drug use + | |||
| Used within 1 month | 7/49 (14) | 4/7 (57) | Ref |
| Used more than 1 month ago | 42/49 (86) | 26/42 (62) | 1.22 (0.24 , 6.17) |
|
| |||
| Depression | |||
| Current depression | 30 (60) | 15/30 (50)# | Ref |
| No current depression | 20 (40) | 16/20 (80)# | 4.00# (1.08 , 14.81) |
|
| |||
| Anxiety disorder | |||
| Current anxiety disorder | 17 (34) | 7/17 (41)# | Ref |
| No current anxiety disorder | 33 (66) | 24/33 (73)# | 3.81# (1.11 , 13.07) |
|
| |||
| IL28B + | |||
| TC or TT | 38 (78) | 20/38 (67)# | Ref |
| CC | 11 (22) | 10/11 (91)# | 9.00# (1.05 , 77.4) |
|
| |||
| Prior treatment + | |||
| Naïve or prior relapser | 4 (8) | 1/4 (25) | Ref |
| Partial or non-responder | 45 (92) | 29/45 (64) | 5.44 (0.52 , 56.7) |
|
| |||
| Cirrhosis | |||
| Cirrhosis | 18 (36) | 9/18 (50) | Ref |
| No cirrhosis | 32 (64) | 22/32 (69) | 1.96 (0.58 , 6.56) |
|
| |||
| Active drug use during treatment + | |||
| Used during treatment | 22/49 (45) | 13/22 (59) | Ref |
| No use during treatment | 27/49 (55) | 17/27 (63) | 1.18 (0.37 , 3.73) |
|
| |||
| DAA Adherence+ | 90.1 ± 0.15 | ||
| < 90% | 13 (29) | 8/13 (62) | Ref |
| ≥ 90% | 32 (71) | 21/32 (66) | 1.19 (0.31 , 4.53) |
+
missing data