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. 2016 Apr 15;11(4):e0153968. doi: 10.1371/journal.pone.0153968

Fig 4. Ghrelin treatment attenuated ischemia-induced p38 phosphorylation and activation.

Fig 4

(A) Gene expression of Mapk14 (p38α) in ghrelin- and saline-treated ischemic buttons at 1, 4 and 20 days post-surgery. Data analyzed by two-way ANOVA multiple comparisons Fisher’s LSD test (* p < 0.05). (B) Peritoneal ischemic buttons from mice treated with ghrelin or saline were subjected to Western blot analysis using antibodies against phospho-p38 MAPK and total p38 MAPK, respectively. (C) The phospho-p38/total p38 protein level ratio was reduced in ghrelin-treated samples (n = 6) compared to the controls (n = 6) at 4 days post-surgery. Data are expressed as mean ± SEM and analyzed by Student’s t-test.