Table 1.
Genes with a significantly expression under steady-state conditions in PAE compared to both C and PF animals (p <0.05) in the PFC (a) and HPC (b) at D16 post-saline injection.
| Table 1a: Genes differentially expressed in PFC of Ethanol-exposed vs. both PF and C animals under steady-state conditions in the microarray.
| ||||||||
|---|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Average Expression | F | p-value | q-value | Fold change
|
||
| Ethanol/Control | Ethanol/Pairfed | Pairfed/Control | ||||||
| H2afv | Rattus norvegicus similar to H2A histone family, member V isoform 1 (LOC685909) | 10.6 | 18.7 | 4.8E-05 | 0.11 | 0.65 | 0.76 | 0.86 |
| Tcf4 | transcription factor 4 | 11.2 | 11.4 | 7.0E-04 | 0.23 | 0.67 | 0.66 | 1.01 |
| Rnasek | ribonuclease, RNase K | 13.2 | 11.1 | 8.0E-04 | 0.23 | 0.68 | 0.57 | 1.19 |
| Ppp1r14a | protein phosphatase 1, regulatory (inhibitor) subunit 14A | 10.0 | 12.6 | 4.1E-04 | 0.23 | 0.68 | 0.64 | 1.05 |
| Rps8 | ribosomal protein S8 | 13.0 | 11.1 | 7.9E-04 | 0.23 | 0.69 | 0.74 | 0.93 |
| ILMN_1372701 | na | 9.4 | 11.3 | 7.3E-04 | 0.23 | 0.71 | 0.79 | 0.90 |
| ILMN_1374168 | na | 9.1 | 10.7 | 9.4E-04 | 0.25 | 0.77 | 0.73 | 1.05 |
| Pex11g | peroxisomal biogenesis factor 11 gamma | 7.0 | 11.5 | 6.7E-04 | 0.23 | 0.82 | 0.71 | 1.16 |
| Ndfip1 | Nedd4 family interacting protein 1 | 11.4 | 12.1 | 5.1E-04 | 0.23 | 1.32 | 1.37 | 0.97 |
| Acsl3 | acyl-CoA synthetase long-chain family member 3 | 10.2 | 12.2 | 4.9E-04 | 0.23 | 1.36 | 1.36 | 1.00 |
| Dusp6 | dual specificity phosphatase 6 | 9.9 | 12.5 | 4.4E-04 | 0.23 | 1.41 | 1.21 | 1.17 |
| Rpl7 | ribosomal protein L7 | 11.6 | 13.7 | 2.7E-04 | 0.22 | 1.44 | 1.36 | 1.05 |
| Med28 | mediator complex subunit 28 | 9.2 | 11.1 | 7.9E-04 | 0.23 | 1.48 | 1.29 | 1.15 |
| Atp6ap1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 11.0 | 10.6 | 9.8E-04 | 0.25 | 1.50 | 1.35 | 1.11 |
| Ap1s2 | adaptor-related protein complex 1, sigma 2 subunit | 9.7 | 12.4 | 4.6E-04 | 0.23 | 1.60 | 1.35 | 1.19 |
| Table 1b: Genes differentially expressed in HPC of Ethanol-exposed vs. both PF and C animals under steady-state conditions in the microarray. | ||||||||
|---|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Average Expression | F | p-value | q-value | Fold change | ||
| Ethanol/Control | Ethanol/Pairfed | Pairfed/Control | ||||||
| Cnih2 | cornichon homolog 2 (Drosophila) | 11.1 | 16.0 | 8.1E-05 | 0.14 | 0.61 | 0.60 | 1.01 |
| Caap1 | caspase activity and apoptosis inhibitor 1 | 9.2 | 15.2 | 1.1E-04 | 0.14 | 0.68 | 0.71 | 0.95 |
| LOC688637 | similar to WD repeat domain 36 | 8.8 | 15.4 | 1.0E-04 | 0.14 | 1.46 | 1.36 | 1.08 |
| Rgs3 | regulator of G-protein signaling 3 | 9.1 | 14.6 | 1.4E-04 | 0.15 | 1.71 | 1.83 | 0.93 |
Bold = p <0.05. na = probe had no specific alignment to current RefSeq RNA database.