Table 2.
Genes identified using Ingenuity Pathway Analysis Upstream Regulator in the PFC (a) and HPC (b) of steady-state animals.
| Table 2a – Upstream Regulator Analysis in the PFC of animals under steady-state conditions
| ||||||||
|---|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Predicted status | Z-score | Overlap p-value | ||||
| PAEvC | PAEvPF | PFvC | PAEvC | PAEvPF | PFvC | |||
| Gast | Gastrin | Activated | 2.1 | 2.2 | NA | 0.05 | 0.009 | 1.00 |
| Lep | Leptin | Activated | 2.5 | 2.6 | NA | 0.12 | 0.04 | 1.00 |
| Table 2b – Upstream Regulator Analysis in the HPC of animals under steady-state conditions
| ||||||||
|---|---|---|---|---|---|---|---|---|
| Gene Symbol | Gene Name | Predicted status | Z-score | Overlap p-value | ||||
| PAEvC | PAEvPF | PFvC | PAEvC | PAEvPF | PFvC | |||
| Ifng | Interferon-gamma | Activated | 3.8 | 2.5 | NA | 0.05 | 0.04 | 1.00 |
| Laminin | Laminin | Activated | 2.0 | 2.0 | NA | 0.01 | 0.04 | 1.00 |
Genes with a Z-score ≥2 or ≤-2 and an overlap p-value ≤0.1 are considered significant (bold). Those with no overlap had a p-value of 1 and no Z-score (NA).