Table 1.
Effect of the AE and EE of the leaves of Albizzia lebbeck with carrageenan-induced paw edema in rats.
| Paw volume (mL) | ||||||
|---|---|---|---|---|---|---|
| Groups | Before | 0 h | 1/2 h | 1 h | 2 h | 3 h |
| Distilled water | 0.97 ± 0.03 | 1.03 ± 0.03 | 1.67 ± 0.07 | 1.97 ± 0.06 | 2.02 ± 0.07 | 1.97 ± 0.04 |
| Diclofenac 20 mg/kg | 1.00 ± 0.04 | 1.07 ± 0.06 | 1.48 ± 0.03* (35.94) | 1.63 ± 0.03* (40.23) | 1.58 ± 0.02* (48.48) | 1.43 ± 0.03* (61.70) |
| AE 50 mg/kg | 0.97 ± 0.04 | 1.07 ± 0.04 | 1.60 ± 0.03 (17.19) | 1.83 ± 0.03 (19.15) | 1.85 ± 0.02* (21.21) | 1.80 ± 0.03* (22.34) |
| AE 100 mg/kg | 0.95 ± 0.03 | 1.02 ± 0.03 | 1.52 ± 0.03 (21.88) | 1.73 ± 0.02* (24.47) | 1.75 ± 0.02* (26.26) | 1.67 ± 0.02* (30.85) |
| AE 200 mg/kg | 0.92 ± 0.03 | 0.98 ± 0.04 | 1.45 ± 0.02* (26.56) | 1.63 ± 0.03* (30.85) | 1.65 ± 0.04* (32.32) | 1.55 ± 0.03* (39.36) |
| EE 50 mg/kg | 0.95 ± 0.03 | 1.07 ± 0.03 | 1.60 ± 0.03 (17.19) | 1.81 ± 0.03* (21.27) | 1.83 ± 0.02* (23.23) | 1.77 ± 0.03* (25.53) |
| EE 100 mg/kg | 1.00 ± 0.03 | 1.07 ± 0.04 | 1.57 ± 0.03 (21.88) | 1.77 ± 0.05* (25.53) | 1.78 ± 0.03* (28.28) | 1.70 ± 0.03* (32.98) |
| EE 200 mg/kg | 0.98 ± 0.03 | 1.08 ± 0.01 | 1.53 ± 0.01 (29.69) | 1.72 ± 0.02* (32.21) | 1.73 ± 0.02* (34.34) | 1.62 ± 0.03* (42.55) |
Values are presented as the mean ± SEM, n = 6 in each group; values given in parentheses represent PI.
One-way ANOVA followed by multiple Tukey's comparison test.
*p < 0.05, as compared to the control group.
AE = aqueous extract of the leaves of A. lebbeck; ANOVA = analysis of variance; EE = ethanolic extract of the leaves of A. lebbeck; PI = percentage inhibition; SEM = standard error of the mean.