Table 1.

Transmission disequilibrium test analyses of TS in the TS sample

Gene	Location*	Marker	Allele	Allele frequency	Transmissions†	Non-transmissions	χ2	P value
KCNJ5	Intron 1	rs7924416‡	C	0.755	69	76	0.338	0.561
			T	0.245	76	69
	Intron 1	rs11221503‡	C	0.802	60	52	0.571	0.449
			T	0.198	52	60
	Intron 1	rs2604212‡	C	0.570	94	90	0.087	0.768
			G	0.430	90	94
	Intron 1	rs11221507	T	0.888	43	34	1.052	0.305
			C	0.112	34	43
	Exon 2 (syn)	rs7118824‡	G	0.834	60	46	1.854	0.173
			T	0.166	46	60
	Exon 2 (nonsyn)	rs7102584	G	0.012	3	5	0.505	0.477
			C	0.988	5	3
	Intron 2	rs11221512‡	A	0.115	36	36	0.000	1.000
			G	0.885	36	36
	3′	rs2604201‡	A	0.279	69	81	0.961	0.327
			G	0.721	81	69
	Intergenic	rs1893142	G	0.307	72	85	1.078	0.299
			A	0.693	85	72
	Intergenic	rs2155548	A	0.770	82	73	0.523	0.469
			C	0.230	73	82

^*Based on NCBI Build 36.1, the March 2006 UCSC human reference sequence.

^†Number of times the alleles were transmitted from heterozygous parents to affected offspring in this sample.

^‡Single nucleotide polymorphism selected using Tagger Pairwise Method (de Bakker et al. 2005).