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. Author manuscript; available in PMC: 2017 Apr 15.
Published in final edited form as: ACS Chem Biol. 2016 Jan 6;11(4):889–899. doi: 10.1021/acschembio.5b00960

Figure 1. Fusicoccadiene synthase from P. amygdali (PaFS).

Figure 1

Geranylgeranyl diphosphate (GGPP) is generated from one molecule of dimethylallyl diphosphate (DMAPP) and three molecules of isopentenyl diphosphate (IPP) in the C-terminal α domain (blue box), and GGPP is cyclized in the N-terminal α domain to form fusicocca-2,10(14)-diene (red box). Further biosynthetic modifications (green) yield the phytotoxin fusicoccin A.