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. Author manuscript; available in PMC: 2017 Apr 18.
Published in final edited form as: Angew Chem Int Ed Engl. 2016 Mar 16;55(17):5337–5341. doi: 10.1002/anie.201511657

Figure 1. Non-canonical selenocysteine assignments in nature.

Figure 1

(A) The tRNASec search pipeline and the manually curated output. The non-canonical tRNASec sequences are grouped by codon recognition; their numbers are given with their (putative) bacterial origins from phylogenetic inference. Green color indicates results from whole genomes, while blue represents results from only metagenomic data. For comparison the number of canonical tRNASecUCA sequences is shown (most of them were not curated). “Y” and “R” denote “C or U” and “A or G”, respectively. (B) Inferred cloverleaf structures of non-canonical tRNASec species. The nucleotide polymorphism among the same tRNASec group is indicated with green letters. The Sec codons and the SECIS elements of formate dehydrogenase mRNAs are shown.