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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Pancreas. 2016 May-Jun;45(5):659–670. doi: 10.1097/MPA.0000000000000522

Figure 4.

Figure 4

Effect of inhibition of PTHrP signaling on the TGF-β-mediated increase in procollagen I (A) and fibronectin (B) mRNA levels in PSCs. Cells were pre-treated with 10−5 M PTHrP (7-34) for 1 h, then treated in the presence of PTHrP (7-34) with TGF-β (3 ng/ml) for 2 h. 10 = primary cells. Procollagen I and fibronectin mRNA levels were measured by reverse transcription/real-time PCR. Values are expressed relative to the control value, set arbitrarily at 1.0. Each bar is the mean ± SEM of three independent experiments. ***, P < 0.001 vs. control; #, P < 0.01 vs. TGF-β alone.