Table III. Domain Scores Associated with Demographic and Clinical Characteristics.
| Mean (SD) | Mean (SD) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Domain | Age | Sex | Genotype | Current hip or joint issues | Pain in past 7 days | |||||
| 8–11 years | 12–17 years | Male | Female | SS/SB0 thalassemia | SC/SB+ thalassemia | Yes | No | Yes | No | |
| Pain interference | 45.8 (14.0) | 50.5 (13.0)** | 46.4 (12.7) | 51.0 (14.1)* | 48.1 (13.5) | 51.0 (14.0) | 57.0 (15.1) | 46.9 (12.6)** | 56.1 (11.8) | 45.4 (13.0)** |
| Fatigue | 44.6 (14.4) | 48.0 (11.9) | 44.6 (12.4) | 48.7 (13.3)* | 46.6 (12.8) | 47.1 (14.0) | 54.5 (13.6) | 45.0 (12.4)** | 53.7 (12.2) | 43.6 (12.2)** |
| Depression | 43.2 (9.7) | 46.2 (10.5)* | 43.1 (8.8) | 46.8 (11.3)** | 44.7 (10.3) | 46.3 (10.4) | 51.1 (10.5) | 43.7 (9.8)** | 48.3 (9.6) | 43.6 (10.3)** |
| Anxiety | 46.3 (12.6) | 44.1 (10.7) | 43.3 (11.3) | 46.6 (11.5) | 44.7 (11.3) | 46.7 (11.9) | 49.4 (14.6) | 44.1 (10.6)* | 50.1 (13.0) | 43.1 (10.4)** |
| Anger | 46.3 (13.1) | 46.0 (12.1) | 45.5 (12.1) | 46.7 (12.9) | 45.3 (11.4) | 48.3 (14.9) | 49.1 (13.3) | 45.7 (12.3) | 46.1 (11.6) | 46.1 (12.8) |
| Mobility | 52.5 (7.7) | 49.2 (8.5)* | 51.6 (8.3) | 49.6 (8.3) | 50.4 (8.6) | 51.0 (7.5) | 43.8 (9.2) | 51.9 (7.6)** | 46.9 (9.8) | 52.4 (6.8)** |
| Upper dexterity | 48.4 (8.1) | 52.0 (6.6)** | 51.9 (6.9) | 49.2 (7.8)** | 50.7 (7.5) | 50.2 (7.6) | 48.1 (8.2) | 51.1 (7.2)* | 48.5 (8.3) | 51.4 (6.9)** |
| Peer relationships | 49.0 (11.2) | 48.1 (10.7) | 47.4 (10.7) | 49.6 (11.1) | 48.7 (11.1) | 47.9 (10.6) | 47.3 (9.8) | 48.7 (11.1) | 47.7 (9.4) | 48.6 (11.3) |
**
p-value < 0.01,
*
p-value <0.05;
SD=Standard Deviation