Skip to main content
. Author manuscript; available in PMC: 2017 Jun 1.
Published in final edited form as: Biomaterials. 2016 Mar 23;92:57–70. doi: 10.1016/j.biomaterials.2016.03.034

Table 2.

Effect of physicomechanical (matrix modulus and fiber) and biomolecular cues (TGF-β1 and BMP-7) on percent normalized change in expression of superficial zone markers for hMSCs encapsulated in Superficial gel.

mRNA expression Protein expression Biochemical measurement
SZP Sox-9 Col II SZP Col II total collagen
TGF-β1 11 ± 8 6 ± 9 4 ± 9 12 ± 5 −3 ± 10 4 ± 5
BMP-7 25 ± 8 21 ± 10 4 ± 9 8 ± 8 −4 ± 12 5 ± 4
optimum matrix modulus 51 ± 7 26 ± 6 −17 ± 4 26 ± 7 −13 ± 11 −5 ± 3
fiber 16 ± 9 25 ± 8 45 ± 9 9 ± 8 28 ± 12 39 ± 8