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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: J Neurosci Methods. 2016 Mar 10;264:136–152. doi: 10.1016/j.jneumeth.2016.02.021

Fig. 7. Effect of changing replenishment rate on the estimated RRP size.

Fig. 7

A. Simulations were performed using the variables N0, p, and R values of {1, 0.2, R}, where R varies from 0.001 to 0.1. The last fifteen points of cumulative EPSCs were fit with a line and backextrapolated to x=0 to measure RRPtrain. B. Plots of the simulated EPSC amplitude versus cumulative EPSC are shown. Linear fits to the first four points of each curve are extended to y=0, indicating the value of RRPEQ. C. The measured pool size as a function of replenishment rate for two methods of RRP estimation: RRPtrain (red) and RRPEQ (blue). The actual RRP size is equal to one (dotted black line).