Scheme 10. Synthesis of Squaric Acid Derivatives.
Reagents and Reaction Conditions: (a) benzylmagnesium bromide, THF, 0 °C to r.t., 40 min, (82%); (b) 3 M HCl, acetone, r.t., 3 h (66%); (c) benzylamine, 200 °C (microwave irradiation), 20 min, (22%).
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