Table IV.
Relation of sociodemographic and clinical factors to the hazard of death after acute myeloid leukaemia by age group at diagnosis, California, 1988–2011
| Characteristics (Total = 3935) |
HR1 (95% CI) 0–9 years N = 964 |
P-value* | HR2 (95% CI) 10–19 years N = 733 |
P-value* | HR3 (95% CI) 20–29 years N = 951 |
P-value* | HR4 (95% CI) 30–39 years N = 1287 |
P-value* |
|---|---|---|---|---|---|---|---|---|
| Calendar period | ||||||||
| 1988–1995 | 1.84 (1.45–2.34) | 1.52 (1.19–1.93) | 1.29 (1.05–1.59) | 1.71 (1.44–2.04) | ||||
| 1996–2003 | 1.36 (1.07–1.73) | 1.27 (0.99–1.63) | 0.95 (0.76–1.18) | 1.14 (0.95–1.36) | ||||
| 2004–2011 | 1.0 (reference) | <0.0001 | 1.0 (reference) | 0.0034 | 1.0 (reference) | 0.0049 | 1.0 (reference) | <0.0001 |
| Race/ethnicity | ||||||||
| Non-Hispanic white | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | ||||
| Non-Hispanic black | 1.22 (0.86–1.74) | 1.19 (0.81–1.74) | 1.70 (1.21–2.39) | 1.19 (0.92–1.54) | ||||
| Hispanic | 1.02 (0.82–1.28) | 1.06 (0.83–1.35) | 1.05 (0.86–1.30) | 1.10 (0.93–1.30) | ||||
| Asian/Pacific Islander | 0.79 (0.57–1.09) | 0.2468 | 1.16 (0.84–1.60) | 0.7294 | 1.28 (0.99–1.64) | 0.0122 | 0.84 (0.67–1.05) | 0.0821 |
| Sex | ||||||||
| Male | 0.93 (0.77–1.12) | 0.89 (0.73–1.08) | 1.17 (0.99–1.38) | 1.06 (0.92–1.21) | ||||
| Female | 1.0 (reference) | 0.4455 | 1.0 (reference) | 0.2287 | 1.0 (reference) | 0.0734 | 1.0 (reference) | 0.4152 |
| Neighbourhood socioeconomic status (quintiles) | ||||||||
| 1. Lowest 20% | 0.88 (0.63–1.22) | 1.11 (0.80–1.53) | 1.26 (0.94–1.68) | 1.19 (0.94–1.51) | ||||
| 2. | 1.07 (0.77–1.47) | 0.96 (0.69–1.32) | 1.03 (0.77–1.38) | 1.21 (0.96–1.53) | ||||
| 3. Middle 20% | 0.86 (0.63–1.20) | 0.93 (0.66–1.30) | 1.14 (0.86–1.52) | 1.31 (1.05–1.53) | ||||
| 4. | 0.83 (0.59–1.17) | 0.82 (0.58–1.16) | 0.84 (0.62–1.14) | 1.31 (1.04–1.64) | ||||
| 5. Highest 20% | 1.0 (reference) | 0.4063 | 1.0 (reference) | 0.4579 | 1.0 (reference) | 0.0583 | 1.0 (reference) | 0.1260 |
| Initial care at hospitals affiliated with NCI-designated cancer centres | ||||||||
| Yes | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | 1.0 (reference) | ||||
| No | 1.10 (0.91–1.32) | 0.3314 | 1.29 (1.03–1.61) | 0.0220 | 1.11 (0.90–1.37) | 0.3310 | 1.31 (1.08–1.58) | 0.0042 |
Abbreviations: HR, hazard ratio; CI, confidence interval; NOS, not otherwise specified; NCI, National Cancer Institute.
*
Likelihood ratio test.