Skip to main content
. 2016 Apr 16;6:33. doi: 10.1186/s13613-016-0138-4

Table 3.

Primary and secondary outcomes

Variables Nebulized heparin (N = 139) Control (N = 147) Odds ratioa (95 % CI) P
Primary outcome
Ventilator-free days at day 28 14.0 (0.0–23.0) 6.0 (0.0–22.0) 0.459
(N = 139) (N = 144)
Secondary outcomes
Overall mortality 34/139 (24.5) 35/147 (23.8) 0.65 (0.50–1.56)b 0.653
(N = 139) (N = 147)
PaO2/FiO2 at day seven (mmHg) 242.5 (206.0–300.0) 220.2 (179.4–297.7) 0.098
(N = 61) (N = 78)
LIS at day seven 2.0 (1.0–2.5) 2.2 (1.7–3.0) 0.027
(N = 40) (N = 48)
Pneumonia during hospital stay 48/82 (58.5) 48/106 (45.3) 1.49 (0.79–2.80) 0.219
(N = 82) (N = 106)
ICU-free days at day 28 2.9 (0.0–19.0) 0.0 (0.0–14.2) 0.035
(N = 78) (N = 62)
Hospital-free days at day 28 0.0 (0.0–12.0) 0.0 (0.0–14.0) 0.951
(N = 139) (N = 147)

Values are median (IQR), and others are no./total no. (%)

Not all requested data were available for each study

LIS lung injury scores, CI confidence interval, N number of patients

aAdjusted by: age and baseline PaO2/FiO2

bPresented as hazard ratio adjusted by: age, %TBSA, and baseline PaO2/FiO2