Model exhibits stationary blebs and nonblebbing states in 2D and 3D. (A) Profile of stationary solution of the 2D system. (Left) Excitable state, in which an initial perturbation (cyan dashed line) expands both in height (normal to the cell surface) and laterally (along the cell surface) before retracting. (Right) Nonexcitable state, in which the initial perturbation rapidly and directly returns to equilibrium. Parameter values are , , , , for the excitable state, and for the nonexcitable state. (B) Profile of the stationary solution of the 3D system in an excitable state. Parameter values are , , , , and . Note that our choice of nondimensionalization means that only relative changes in and are physically meaningful. To see this figure in color, go online.