Table 3. Decrease in mean peak height (± SD), compared with control (untreated skin) of C=O stretching (Amide I)and C-N stretching of keratin(Amide II )absorbance of abdominal hydrated whole skin rat following treatment with different vehicles (mean ± SD, n = 3) .
vehicles | C=O stretching of keratin | C-N stretching of keratin | ||
Peak height | %D | Peak height | %D | |
Control | 4.952±0.021 | - | 4.840+0.045 | - |
PG | 0.012±0.002 | 99.75±1.211 | 0.007±0.0003 | 99.85±2.18 |
Span 80 | 1.725±0.089 | 65.16±1.15 | 1.953±0.053 | 59.64±1.71 |
Tween 80 | 1.774±0.011 | 64.17±2.05 | 1.806±0.007 | 62.68±1.92 |
Labrafac PG | 1.806±0.026 | 63.52±1.88 | 1.857±0.013 | 61.63±1.58 |
Transcutol P | 1.555±0.064 | 68.598±2.014 | 1.719±0.037 | 64.48±1.71 |