Table 2.

Definition of "symptomatic UTI" as primary endpoint for ProSCIUTTU (need to refer to Fig. 2). Use the following table to assess “Category 1”, or Two “Category 2” and any “Category 3” Symptoms: All symptoms should be asked in each category

“Category 1” Symptoms:*	“Category 2” Symptoms:*	“Category 3” Symptoms:
	Two or more	In themselves not enough to lead to treatment but recorded for International Spinal Cord Injury Urinary Tract Infection Datasets Compatibility
• Temperature: Greater than 38 ° C core Greater than 37.5 ° C per axilla • New or increasing symptoms of Autonomic Dysreflexia, as detected by any of the following signs: Pulse < 50 or increased flushing or sweating or headache AND increased B.P Diastolic or Systolic > 25 % usual baseline.	• Increased Frequency of Muscle Spasms or spasticity • Failure of usual control of urinary incontinence- any of the following constitutes fulfillment of this category -Bladder Spasm -Urinary frequency or need for increased catheterization -Urinary Retention -Urinary Urgency -Leaking around catheter site or per urethra if have suprapubic catheter • New Scrotal/Loin/Abdominal Discomfort unexplained by other pathology - any of the following constitutes fulfillment of this category -Abdominal Pain -Bladder/Suprapubic Pain -Loin/Back Pain -Scrotal Pain -Dysuria	any of the following constitutes fulfillment of this category -Anxiety/uneasiness -Feeling tired -Feeling sick -Arthralgias/Body Aches -Chills -Diaphoresis/sweating -Cloudy Urine -Foul smelling urine -Blood in urine haematuria -Catheter blockage

*Content adapted and modified from Box 1 of Spinal-injured neuropathic bladder antisepsis (SINBA) trial [4]