Table 2.
Prediction of early preterm delivery in women who had undergone cerclage for cervical shortening. Results of the univariate and multivariate analysis
| Univariate analysis | Multivariate analysis | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Delivery <35 week (n = 19) | Delivery ≥35 week (n = 37) | OR (95 % CI)a | P | P | Adjusted OR (95 % CI) a | P | P | ||
| (Wald’s test) | (LR test)b | (Wald’s test) | (LR test)b | ||||||
| Age (years)c | 33 (27;38) | 31 (29;36) | 1.01 (0.92,1.12) | 0.758 | 0.757 | - | - | - | |
| Body mass index (kg/m2)c | 24.8 (21.0; 30.4) | 23.2 (20.2;27.2) | 1.09 (0.96,1.23) | 0.189 | 0.183 | - | - | - | |
| Previous preterm deliveryd | 7 (36.8) | 22 (59.5) | 0.4 (0.13,1.24) | 0.113 | 0.107 | - | - | - | |
| Previous second trimester miscarriaged | 13 (68.4) | 20 (54.1) | 1.84 (0.58,5.9) | 0.304 | 0.297 | - | - | - | |
| Previous conizationd | 3 (15.8) | 9 (24.3) | 0.33 (0.09,1.21) | 0.094 | 0.072 | - | - | - | |
| Pregnancy after IVF treatmentd | 3 (15.8) | 2 (5.4) | 3.28 (0.5,21.6) | 0.217 | 0.211 | - | - | - | |
| Urinary tract infection during pregnancyd | 0 (0) | 1 (2.7) | 0 (0,Inf) | 0.992 | 0.360 | - | - | - | |
| Parityc | 0 | 8 (42.1) | 4 (10.8) | reference | reference | 0.292 | - | - | - |
| 1 | 6 (31.6) | 15 (40.5) | 0.33 (0.02;5.03) | 0.427 | - | - | - | ||
| ≥2 | 5 (26.3) | 18 (48.6) | 0 (0;inf) | 0.996 | - | - | - | ||
| Cigarette smokingd | 3 (15.8) | 7 (18.9) | 0.8 (0.18,3.54) | 0.772 | 0.770 | - | - | - | |
| Gestational age at cerclagec | 16 (16;18) | 16 (16;18) | 1.14 (0.66,1.96) | 0.634 | 0.633 | - | - | - | |
| CLe before cerclage (mm)c | 17 (14;20) | 23 (17;24) | 0.89 (0.8,0.99) | 0.036 f | 0.028 f | 0.98 (0.86,1.13) | 0.808 | 0.809 | |
| CLe after cerclage (mm)c | 14 (9;19) | 27 (22;32) | 0.82 (0.74,0.91) | <0.001 f | <0.001 f | 0.85 (0.73,0.99) | 0.041 | 0.024 f | |
| Decrease in CLe after cerclaged | 13 (68.4) | 7 (18.9) | 9.29 (2.61,33.06) | <0.001 f | <0.001 f | Not included due to redundancy | |||
| CLe at the 20 gestational week (mm)c | 16 (10;23) | 24 (21;31) | 0.84 (0.76,0.93) | 0.001 | <0.001 f | 0.98 (0.82,1.16) | 0.803 | 0.803 | |
| CLe at the 22 gestational week (mm)c | 15 (5;23) | 20 (16;29) | 0.89 (0.83;0.97) | 0.007 | 0.002 f | 0.97 (0.87,1.08) | 0.595 | 0.593 | |
a OR (95 % CI) = odds ratio (95 % confidence interval), b LR test = likelihood ratio test, c Continuous variable, provided in median (interquartile range); d nominal variable, provided in n (%); e CL = cervical length; f Italic letters indicate statistical significance; g despite its significant predictive value in the univariate analysis, the parameter “cervical length before cerclage” was not included in the multivariate model due to its co-linear association with the parameter “cervical length after cerclage” that was more predictive in the univariate analysis