Table 3.
Major Clinicopathological Features of 9 Patients with OS > 60 Months
| No. | Age (Years) | P/R | Histopathology | CRS⁎ | HIPEC | PCI | CC | OS/PFS (Months) | Comments |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 43 | P | Serous-mucinous cystadenocarcinoma, moderately differentiated | Resection of pelvic peritoneum, anterior wall peritoneum, hysterectomy and resection of bilateral ovarian/fallopian tube, mesenteric fulguration | DDP 100 mg/m2, MMC 20 mg/m2 | 15 | 0 | 70.0/70.0, DFS | Comorbidity: poliomyelitis sequel period, polycystic liver, and polycystic kidney |
| 2 | 62 | P | Serous papillary adenocarcinoma, moderately differentiated | Right diaphragmatic copula peritoneum, left/right paracolic sulci peritoneum, pelvic peritoneum, liver round ligament resection, hysterectomy and resection of ovarian/fallopian tube | DDP 100 mg/m2, MMC 20 mg/m2 | 19 | 1 | 74.5/16.5, SWT | Pleurectomy and hyperthermic intrathoracic chemotherapy were conducted 2 years after CRS+HIPEC due to pleural metastasis |
| 3 | 32 | P | Mucinous cystadenocarcinoma, well differentiated | Resection of bilateral ovarian/fallopian tube, pelvic peritoneum, and liver round ligament | DDP 100 mg/m2, MMC 20 mg/m2 | 15 | 0 | 72.5/72.5, DFS | |
| 4 | 49 | R | Serous papillary adenocarcinoma, moderately-poorly differentiated | Sigmoidectomy, rectectomy, resection of pelvic peritoneum | DDP 100 mg/m2, MMC 20 mg/m2 | 11 | 1 | 75.5/72.5, DFS | |
| 5 | 57 | R | Borderline serous cystadenocarcinoma, moderately differentiated | Resection of right paracolic sulci peritoneum, pelvic peritoneum, anterior wall peritoneum | DDP 100 mg/m2, MMC 20 mg/m2 | 16 | 0 | 76.6/18.0, D | |
| 6 | 50 | R | Serous papillary adenocarcinoma, moderately-poorly differentiated | 1st: ileectomy, resection of anterior wall peritoneum 2nd: resection of pelvic peritoneum, anterior wall peritoneum and bilateral fossa iliaca peritoneum, mesenteric fulguration |
1st: DDP 100 mg/m2, MMC 20 mg/m2, 2nd: Lobaplatin 50 mg/m2, TAX 100 mg/m2 | 1st: 20 2nd: 22 | 1st: 1 2nd: 2 |
65.3/8.5, D | Intraperitoneal extensive bowel adhesions were found at the second operation |
| 7 | 67 | R | Endometrioid carcinoma, poorly differentiated | Resection of right paracolic sulci peritoneum, right diaphragmatic copula peritoneum, pelvic peritoneum, anterior wall peritoneum | DDP 100 mg/m2, MMC 20 mg/m2 | 16 | 1 | 204.0/54.0,D | A total of 4 operations and 2 TACEs were implemented from first treatment to death |
| 8 | 51 | R | Borderline mucinous cystadenocarcinoma, moderately differentiated | Resection of left/right diaphragmatic copula peritoneum, left/right paracolic sulci, pelvic peritoneum and bilateral fossa iliaca peritoneum | DDP 100 mg/m2, MMC 20 mg/m2 | 22 | 1 | 79.5/16.0, D | SAE: small intestinal leakage, abdominal infection (Proteus mirabilis infection) |
| 9 | 60 | R | Mucinous cystadenocarcinoma, moderately differentiated | 1st: greater/lesser omentectomy, appendicectomy 2nd: resection of ileocecum, left/right diaphragmatic copula peritoneum and ascending colon |
1st: DDP 100 mg/m2, MMC 20 mg/m2, 2nd: Lobaplatin 50 mg/m2, TAX 100 mg/m2 | 1st: 5 2nd: 8 | 1st: 0 2nd: 0 |
122.7/58.0,DFS | Comorbidity: hypertension; type 2 diabetes mellitus |
P, primary; R, recurrent; DDP, cis-platinum; TAX, paclitaxel; TACE, transcatheter arterial chemoembolization; DFS, disease-free survival; SWT, survival with tumor; D, died.
PFS was calculated from the first CRS+HIPEC in this table.
⁎
Greater omentectomy and lesser omentectomy were performed on all the nine patients.