Table 2.
Effect of adropin on blood glucose, HbA1c (%), HOMA-IR, HOMA-β and serum insulin levels of control, hyperlipidemic, adropin treatment groups of rats
| Groups | C (n=8) | H (n=8) | A (n=8) | P |
|---|---|---|---|---|
| Blood glucose (mg/dl) | 101.8 ±16.3ab | 235.2 ±29.1ac | 154.0 ±13.6bc | 0.010 |
| HbA1c (%) | 0.95 ±0.16a | 2.05 ±0.16ab | 1.00 ±0.02b | 0.001 |
| HOMA-IR | 20.6 ±3.76a | 73.5 ±12.2ab | 29.6 ±7.86b | 0.006 |
| HOMA-β | 5892.6 ±2730.0ab | 205.0 ±21.9a | 258.4 ±76.5b | 0.002 |
| Insulin (nIU/ml) | 103.4 ±13.2a | 127.2 ±10.0b | 61.8 ±8.76ab | 0.009 |
C: control, H: hyperlipidemic, A: adropin treatment groups; P: Shows the differences between all groups (Kruskal-Wallis test)
a,b,c
In each line, the difference between the means with same letters are significant, P≤0.05 (Mann-Whitney U test)