Table 1. Phenotypic Characteristics of VSSA, hVISA, and VISA Isolates.
VSSA (n = 51) | hVISA (n = 34) | VISA (n = 45) | P Valuea | P Valueb | P Valuec | |
---|---|---|---|---|---|---|
PAP-AUC ratio, range (mean ± SD) | 0.12 - 0.88 (0.62 ± 0.16) | 0.90 - 1.27 (1.04 ± 0.12) | 1.35 - 3.91 (1.92 ± 0.66) | < 0.001d | < 0.001d | < 0.001d |
Vancomycin MIC range (MIC 50/90 ), μg/mL | 1 - 2 (1/2) | 1 - 3 (1/2) | 2 - 16 (14/16) | 0.040d | < 0.001d | < 0.001d |
Coagulase negative after 24 hours incubation, No. (%) | 0 | 4 (11.8) | 9 (20) | 0.023e | < 0.001e | 0.375e |
agr -dysfunction by colony spreading assay, No. (%) | 15 (29.4) | 14 (41.2) | 25 (55.6) | 0.351e | 0.013e | 0.258e |
OD 560 value of urease activity, Mean ± SD | 0.369 ± 0.25 | 0.345 ± 0.33 | 0.559 ± 0.32 | 0.701d | 0.002d | 0.005d |
Abbreviations: hVISA, heterogeneous vancomycin-intermediate
aP value when comparing the results of hVISA with those of VSSA.
bP value when comparing the results of VISA with those of VSSA.
cP value when comparing the results of hVISA with those of VISA.
dStudent t-test.
eFisher’s exact test.