Table 3.

System‐specific input parameters for the central lung, peripheral lung, and the nose

Parameter	Central lung	Peripheral lung	Nose
Blood flow (fraction of Q CO)	0.021a	1	0.0015b
Surface area (dm2/kg)	3.27c	276.4d	0.416e
Lining fluid volume (µL/kg)	163.6a	193.5a	20.8a
Fraction of tissue volume	0.19a	0.81a	NA
k mcc (h−1)	0.0472f	NA	0.2079

k_mcc, rate constant for mucociliary clearance; NA, not available; Q_CO, cardiac output.

^a*Calculations of the lining fluid volume and tissue fractions are provided in the Supplementary Material; References: a) Ref. 21; b) Ref. 22; c) Ref. 31 (normalized per kg); d) Ref. 32 (normalized per kg); e) Ref. 33 (normalized per kg); f) Ref 30.