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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Neurochem Res. 2015 Dec 8;41(5):1042–1049. doi: 10.1007/s11064-015-1790-z

Fig. 1.

Fig. 1

Effect of MPP+ on CCL2 release from mouse primary mast cells obtained from wild-type mice. BMMCs obtained from wild-type mice were infected with Ad5CMV GMF to overexpress GMF or Ad5CMV cytoLacZ as control. These cells were then incubated with or without MPP+ (10 μM) for 24 h at 37°C. CCL2 levels were measured in the supernatant media were by ELISA (n=6). MPP+ significantly increased the release of CCL2 from BMMCs. MPP+ also increased CCL2 release from LacZ V and GMF-V infected BMMCs when compared with their respective MPP + untreated conditions. BMMCs released more CCL2 after GMF overexpression with GMF -V when compared to LacZ-V control. *=p<0.05, compared to respective unstimulated control cells, ANOVA and Tukey-Kramer.