Table 4.
Extrapolation of key results to national epidemiological data
If WLST-N<72 were eliminated: | |||||||
---|---|---|---|---|---|---|---|
EMS-treated out-of-hospital cardiac arrests |
→ | Surviving to hospital |
→ | Exposed to WLST-N<72 |
Predicted outcome without exposure | Lives annually | % Improvement in outcomes |
321 mil × 52.1/100K[18] = 167,000 | × | 0.25[17] = 41,750 | × | 0.22 = 9,185 | Survival | ||
Propensity match: 0.25 (0.22 –0.28) | 2,296 (2,021– 2,572) | 5.5% (4.8% – 6.2%) | |||||
Logistic regression model: 0.26 (0.23 – 1.0) | 2,388 (2,113 – 9,185) | 5.7% (5.1% – 100%) | |||||
Favorable outcome | |||||||
Propensity match: 0.16 (0.14 – 0.19) | 1,470 (1,286 – 1,745) | 3.5% (3.1% – 4.2%) | |||||
Logistic regression model: 0.16 (0.14 – 1.0) | 1,470 (1,286 – 9,185) | 3.5% (3.1% – 100%) |
Abbreviations: EMS – Emergency medical services; WLST-N<72 - Withdrawal of life-sustaining therapy because of perceived neurological injury and assumed poor prognosis before 72 hours of return of spontaneous circulation