Table 1. Baseline Characteristics for Study Population with T1D.
| Men (n=298) | Women (n=354) | P-value | |
|---|---|---|---|
| Age (years) | 37 ± 9 | 36 ± 9 | 0.07 |
| Diabetes duration (years) | 24 ± 9 | 23 ± 9 | 0.29 |
| HbA1c (%) | 8.0 ± 1.2 | 8.0 ± 1.3 | 0.88 |
| HbA1c (mmol/mol) | 64 ± 13 | 64 ± 14 | 0.88 |
| LDL-C (mg/dl) | 104 ± 30 | 98 ± 28 | 0.006 |
| HDL-C (mg/dl) | 51 ± 14 | 60 ± 17 | <0.0001 |
| Triglycerides (mg/dl) | 80 (61-113) | 77 (61-104) | 0.23 |
| Systolic BP (mm Hg) | 121 ± 14 | 114 ± 14 | <0.0001 |
| Diastolic BP (mm Hg) | 80 ± 9 | 75 ± 8 | <0.0001 |
| BMI (kg/m2) | 26.5 ± 3.9 | 26.0 ± 4.7 | 0.09 |
| Waist circumference (cm) | 90.3 ± 11.7 | 80.8 ± 12.0 | <0.0001 |
| AER (μg/min) | 7.4 (4.5-23.8) | 5.8 (3.8-11.8) | <0.0001 |
| eGFRCREASTININE at baseline (mL/min/1.73m2) | 100 ± 27 | 105 ± 28 | 0.02 |
| eGFRCREATININE at year 6 (mL/min/1.73m2) | 97 ± 22 | 99 ± 21 | 0.36 |
| eGFRCYSTATIN C at baseline (mL/min/1.73m2) | 107 ± 23 | 106 ± 20 | 0.68 |
| eGFRCYSTATIN C at year 6 (mL/min/1.73m2) | 102 ± 23 | 102 ± 20 | 0.96 |
| eIS (mg/kg-1 min-1) | 3.8 ± 1.4 | 4.8 ± 1.6 | <0.0001 |
| On antihypertensive medications (%) | 41% | 35% | 0.08 |
| Ever smoker (% yes) | 18% | 22% | 0.20 |
| Albuminuria (% yes) | 27% | 17% | 0.005 |
| PDR (% yes) | 27% | 19% | 0.02 |
| Retinopathy (% yes) | 33% | 26% | 0.07 |
Data are means ± SD, % or median (25th – 75th %)