Table 2. Heart failure with preserved ejection fraction (HFpEF) specific characteristics and pharmacotherapy.
Disease-specific characteristics | |
NYHA Class II | 11 (52%) |
NYHA Class III | 8 (38%) |
NYHA Class IV | 2 (10%) |
Diabetic | 10 (48%) |
Hypertensive | 17 (81%) |
Echocardiographic and Doppler analysis | |
Left ventricular ejection fraction (%) | 61 ± 1 |
E-wave velocity (cm/s) | 89 ± 8 |
A-wave velocity (cm/s) | 100 ± 11 |
E/A ratio | 1.14 ± 0.19 |
E/E′ (medial) | 19 ± 3 |
E/E′ ratio (lateral) | 13 ± 2 |
Mitral E-wave deceleration time (ms) | 216 ± 19 |
Functional capacity | |
Six min walk (m) | 414 ± 68 |
Gait speed (m/s) | 0.94 ± 0.07 |
Medications | |
β blocker | 9 (43 %) |
ACEi or ARB | 8 (38%) |
Loop diuretic | 20 (95%) |
Aldosterone antagonist | 14 (67%) |
Statin | 16 (76%) |
Nitrates | 5 (24%) |
New York Heart Association, NYHA.