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. 2016 Apr 18;7:134. doi: 10.3389/fimmu.2016.00134

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Copyright © 2016 Lu, Chen, Lai, Lai, Fang, Dao, Kang, Fan, Guo, Fu and Andrieu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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CD8⁺ T-cell (rather than NK cell)-mediated viral suppression in 10 elite controllers (ECs) and 10 patients with high viral load (HVLpts). (A) Suppression of HIV-1 replication in autologous CD4⁺ T cells by CD8⁺ T cells purified (by negative selection) from fresh PBMCs. (B) By fresh PBMCs depleted of CD8 or CD16/56.