Figure 3.

Functional features of CD8⁺ T-cell-mediated viral suppression. (A) CD8⁺ T-cell-mediated viral suppression (green) was reduced by nearly 3 logs when freshly purified CD8⁺ T cells were added 48 h after SEB and anti-CD3/28 stimulation (red). (B) CD8⁺ T-cell-mediated viral suppression (green) was reduced by 2.5 logs when CD8⁺ T cells were separated in a transwell culture (red). (C) No cytotoxicity was observed in autologous HIV-1-infected CD4⁺ T cells (target cells) co-incubated with CD8⁺ T-cells (effector cells) from ECs No. 1–5.