Table 1.
Serological motifs | Class I type and allelesa | Amino-acid position (numberb in ECs/HVLpts) |
||||
---|---|---|---|---|---|---|
77 | 80 | 81 | 82 | 83 | ||
Bw4 | HLA-A/B A*2402, B*1302, B*1513, B*2702, B*2704, B*3802, B*5101, B*5102, B*5201, B*5301, B*5801 |
Asn (9/3)* | Ile (9/1)** Thr (0/2) |
Ala (9/3)* | Leu (9/3)* | Arg (9/3)* |
Bw6 | HLA-B B*1501, B*1502, B*1512, B*1532, B*3505, B*4001, B*4002, B*4601, B*4801, B*5401, B*5502 |
Ser (5/10)* | Asn (5/10)* | Leu (5/10)* | Arg (5/10)* | Gly (5/10)* |
*P < 0.05 (Fisher’s exact test was performed on the frequency comparison of single amino-acid position between ECs and HVLpts).
**P < 0.01.
aOnly alleles observed in the individuals who participated in the study.
bThe number of individuals (either homozygous or heterozygous for Bw4 or Bw6) showing a particular amino acid at each HLA-I position.