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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Metabolism. 2016 Jan 14;65(5):634–645. doi: 10.1016/j.metabol.2016.01.005

Figure 4. Therapeutic Potential for AMPK-Combination Therapies in Overnutrition.

Figure 4

Autophagy is inversely associated with ER, oxidative and inflammatory stresses which increase risk for metabolic disease. Panels 1-3 use autophagy as an example to illustrate the potentially improved suppression of these stresses by targeting both AMPK and mTORC1.