Table 2.
Diagnostic differences in gyrification (threshold for inclusion in a cluster, p=0.05).
| Cortical region | Talairach coordinates of the centroid (x,y,z) | Cluster size (mm2) | Clusterwise probability |
|---|---|---|---|
| Reduced surface area in patients | |||
| Right dorsolateral prefrontal (BA 9, BA 10, BA 46) | 23.6, 48.9, 15.1 | 1490 | 0.002 |
| Left dorsolateral prefrontal (BA 9, BA 10, BA 46) | −18.4,−8.1, 54.5 | 1041 | 0.04 |
| Increased surface area in patients None | |||
| Structural covariance in patients | |||
| Left dorsolateral frontal (BA 10, BA 46, BA 47) | −33.1, 50.0, 0.5 | 975 | 0.0001 |
| Right precuneus (BA 31) | 8.4, −66.6, 39.2 | 689 | 0.0001 |
| Left medial frontal (BA 24, BA 32) | −11.3, 36.6, −9.7 | 617 | 0.0004 |
| Right posterior cingulate (BA 24) | 4.7, 1.0, 35.0 | 461 | 0.005 |
| Right dorsolateral frontal (BA 10) | 23.9, 47.1, 13.5 | 397 | 0.012 |
| Right postcentral (BA 43) | 57.9, −12.8, 27.9 | 338 | 0.033 |
| Right medial frontal (BA 32) | 11.2, 35.1, −9.5 | 331 | 0.036 |
| Right superior temporal (BA 22) | 62.7, −33.0, 7.5 | 317 | 0.044 |
| Structural covariance in controls None | |||
Note : L BA, Brodmann area.