Table 1.
MICs of Daptomycin-Susceptible Parent Strains (T48082 and W40308) and Daptomycin-Resistant Derivatives (S32472 and W49297)
| MIC (mg/L) | ||||
|---|---|---|---|---|
| Patient No. 1 | Patient No. 2 | |||
| T48082 | S32472 | W40308 | W49297 | |
| Ampicillin | 2 | 2 | 32 | 32 |
| Ceftriaxone | 8 | 8 | >32 | >32 |
| Ciprofloxacin | >32 | >32 | >32 | >32 |
| Clindamycin | >256 | >256 | >256 | >256 |
| Daptomycin | 0.064 | >256 | 0.125 | >256 |
| Erythromycin | 16 | 8 | >256 | 32 |
| Gentamicin | 4 | 4 | 0.064 | 0.5 |
| Linezolid | 0.25 | 0.5 | — | 0.25 |
| Penicillin | 1 | 0.5 | >32 | 16 |
| Tetracycline | 64 | 64 | 64 | 32 |
| Vancomycin | 0.5 | 0.5 | 0.5 | 1 |
MICs were determined by Etest.® Daptomycin MICs were confirmed by macrobroth dilution.
MIC, minimum inhibitory concentration.