Table 1.
Animal | Treatment | Source of gDNA | Changes in bulge A (excluding other mutations such as recombination) |
---|---|---|---|
1 | i.v. Toca 511 | Thymus | Contraction of 7(A) to 6(A) in IRES accompanied by deletion in CD |
Expansion of 7(A) to 8(A) in IRES | |||
Expansion of 7(A) to 9(A) in IRES | |||
2 | i.v. Toca 511 | Lymph node | Expansion of 7(A) to 10(A) in IRES |
Expansion of 7(A) to 11(A) in IRES | |||
3 | i.v. Toca 511 | Thymus | Expansion of 7(A) to 8(A) in IRES |
IRES, internal ribosome entry site; gDNA, genomic DNA.