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. 2016 Apr 18;6:24168. doi: 10.1038/srep24168

Figure 1. Maternal high-fat diet (HFD) feeding during lactation induces early postnatal hyperalimentation (pHA), early-onset overweight and increased white adipose tissue (WAT) in the murine offspring.

Figure 1

(A) Body weight gain (gram) from postnatal day 1 (P1) to P21. Early postnatal hyperalimentation (open square; n = 36 from 9 litters; pHAmouse group), Ctrl (solid square; n = 30 from 6 litters; Ctrl). (B) Body weight (gram) at P70 (Ctrl: n = 21 from 7 litters; pHAmouse: n = 18 from 6 litters). (C) WAT weight (gram) relative to body weight (gram) at P21 (Ctrl: n = 10 from 5 litters; pHAmouse: n = 11 from 6 litters) and at P70 (Ctrl: n = 11 from 6 litters; pHAmouse: n = 17 from 7 litters). pHAmouse group: white bar, Ctrl: black bar. Mean ± SEM; two way ANOVA test and Bonferroni posttest (A), Mann Whitney test. (B,C); *p < 0.05, **p < 0.01, ***p < 0.001; n.s. = not significant.