Table 2.
Demographics of external dataset
| Characteristics | Mean ± SD | Median (Range) |
|---|---|---|
| Number of recipients (Samples) * | 52(609) | / |
| by Male/Female * | 35/17 (441/168) | / |
| Age (years) | 38.9 ± 8.6 | 39.4 (21.9–61.2) |
| Height (cm) | 168.3 ± 6.6 | 170.0 (150.0–180.0) |
| Total body weight (kg) | 59.7 ± 9.5 | 59.5 (39.5–86.3) |
| Fat‐free mass (kg) | 46.8 ± 8.7 | 49.3 (28.9–63.3) |
| Postoperative time (days) | 37.6 ± 25.7 | 32.0 (3.0–90.0) |
| Tacrolimus daily dose (mg day–1) | 4.6 ± 1.8 | 5.0 (1.0–8.0) |
| Tacrolimus daily dose (mg kg–1 day–1) | 0.078 ± 0.032 | 0.078 (0.017–0.203) |
| Trough concentration (ng ml−1) | 6.6 ± 2.9 | 6.3 (2.1–26.1) |
| Haemoglobin (g l−1) | 114.6 ± 20.5 | 115.0 (57.0–155.0) |
| Haematocrit (%) | 34.7 ± 6.1 | 34.9 (17.6–47.6) |
| Albumin (g l−1) | 41.3 ± 6.0 | 42.0 (22.0–52.0) |
| Globulin (g l−1) | 25.2 ± 3.8 | 25.0 (11.0–37.0) |
| Aspartate transferase (U l−1) | 22.5 ± 17.5 | 18.0 (7.0–187.0) |
| Total protein (g l−1) | 66.5 ± 7.6 | 68.0 (38.0–81.0) |
| Total bilirubin (μmol l−1) | 8.8 ± 4.4 | 7.9 (2.0–38.9) |
| Serum creatinine (μmol l−1) | 109.7 ± 43.9 | 105.0 (47.0–481.0) |
| Creatinine clearance (ml min−1) † | 69.7 ± 17.4 | 69.4 (10.9–115.8) |
| Blood uric nitrogen (mmol l−1) | 8.9 ± 4.5 | 7.8 (3.2–42.2) |
| Oral prednisone daily dose (mg day–1) | 21.6 ± 14.3 | 20.0 (0.0–80.0) |
| Concomitant calcium channel blocker * | 50 (513) | / |
| Nicardipine * | 14 (24) | / |
| Diltiazem * | 0 | / |
| Diabetes mellitus * | 4 (18) | / |
*
Data are expressed as number of recipients (samples).
†
Using Cockcroft–Gault formula: CLcr = [(140 − Age (years)) × Total body weight (kg)]/(0.818 × Scr (μmol l−1)) × (0.85, if female)