Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Apr 14;7:11248. doi: 10.1038/ncomms11248

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Nature Publishing Group, a division of Macmillan Publishers Limited. All Rights Reserved.

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) A cartoon representation of the domain structure of ATX combined with a transparent surface highlighting the position of tunnel; the SMB domains are coloured in pink and magenta, the PDE domain in green, the NUC domain in blue, the lasso loop wrapping around the NUC domain in orange and the short loop connecting the SMB domains to the PDE domain in cyan; the zinc ions are shown as spheres; a yellow background highlights the tunnel site, (b) the same cartoon model, with bound LPA18:1 (PDB:3NKP) and a yellow circle designating the tunnel site. All structural images were generated using PyMOL (http:// www.pymol.org) or CCP4mg⁴⁸.