Figure 1.
Result of BCATm screen of the DNA encoded benzimidazole library and the generic structures of the two BCATm hit series I and II, where BB1, BB2, and BB3 refer to cycle 1, 2, and 3 building blocks, respectively. Compounds on line 1 and line 2 share common BB1 and BB3 as indicated in their corresponding frames with BB2 as a variable component. The size of a dot is proportional to the DNA tag copy number. Library members with a single copy were removed to simplify visualization. An enlarged Figure 1 can be found in the SI section.