Table IV.

Univariate and Multivariate Analysis of Complete Remission and Overall Mortality.

	Complete Remission				Mortality
	Univariate		Multivariate		Univariate		Multivariate
Characteristic	OR (95%CI)	p	OR (95%CI)	p	HR (95% CI)	p	HR (95% CI)	p
Age
<60 years	1.0		1.0		1.0		1.0
≥ 60 years	2.0 (0.5–8.8)	0.36	2.6 (0.5–15)	0.29	1.8 (0.8–4.0)	0.14	1.8 (0.8–4.1)	0.18
Cytogenetics
Good/Intermediate	1.0		1.0		1.0		1.0
Worst	1.5 (0.4–5.1)	0.52	1.9 (0.4–9.5)	0.45	1.3 (0.6–2.6)	0.55	1.4 (0.6–3.1)	0.41
Duration of First CR
≥ 38 weeks	1.0		1.0		1.0		1.0
1–37 vs ≥ 38 weeks	0.2 (0.0–1.0)	0.04	0.1 (0.0–1.0)	0.05	3.4 (1.3–8.9)	0.01	4.4 (1.5–13)	0.007
0	0.6 (0.1–3.6)	0.56	0.5 (0.0–6.0)	0.56	1.0 (0.3–2.6)	0.93	1.4 (0.4–4.4)	0.60
Salvage number
1st	1.0		1.0		1.0		1.0
2nd	0.6 (0.1–2.6)	0.46	0.5 (0.1–3.0)	0.44	3.2 (1.4–7.4)	0.006	3.6 (1.4–9.1)	0.008
>2nd	0.1 (0.0–1.2)	0.07	0.1 (0.0–1.6)	0.09	4.9 (1.7–14)	0.003	7.3 (2.2–24)	0.001
Secondary AML
No	1.0		1.0		1.0		1.0
Yes	0.3 (0.1–0.9)	0.04	0.2 (0.0–1.1)	0.06	1.3 (0.6–2.8)	0.48	1.4 (0.6–3.3)	0.40

Characteristic	CR Odds ratio (95% CI)		Mortality Hazard ratio (95%CI)		Univariate p		Multivariate p
	Univariate	Multivariate	Univariate	Multivariate	CR	Mortality	CR	Mortality
Age
<60 years	1.0	1.0	1.0	1.0
≥ 60 years	2.0 (0.5–8.8)	2.6 (0.5–15)	1.8 (0.8–4.0)	1.8 (0.8–4.1)	0.36	0.14	0.29	0.18
Cytogenetics
Good/Intermediate	1.0	1.0	1.0	1.0
Worst	1.5 (0.4–5.1)	1.9 (0.4–9.5)	1.3 (0.6–2.6)	1.4 (0.6–3.1)	0.52	0.55	0.45	0.41
Duration of First CR
≥ 38 weeks	1.0	1.0	1.0	1.0
1–37 vs ≥ 38 weeks	0.2 (0.0–1.0)	0.1 (0.0–1.0)	3.4 (1.3–8.9)	4.4 (1.5–13)	0.04	0.01	0.05	0.007
0	0.6 (0.1–3.6)	0.5 (0.0–6.0)	1.0 (0.3–2.6)	1.4 (0.4–4.4)	0.56	0.93	0.56	0.60
Salvage number
1st	1.0	1.0	1.0	1.0
2nd	0.6 (0.1–2.6)	0.5 (0.1–3.0)	3.2 (1.4–7.4)	3.6 (1.4–9.1)	0.46	0.006	0.44	0.008
>2nd	0.1 (0.0–1.2)	0.1 (0.0–1.6)	4.9 (1.7–14)	7.3 (2.2–24)	0.07	0.003	0.09	0.001
Secondary AML
No	1.0	1.0	1.0	1.0
Yes	0.3 (0.1–0.9)	0.2 (0.0–1.1)	1.3 (0.6–2.8)	1.4 (0.6–3.3)	0.04	0.48	0.06	0.40