Table 3. Lung Volumes at Fixed Pressures.
Groups | Volume at −10 cm H2O (mL) | Volume at 0 cm H2O (mL) | Volume at 5 cm H2O (mL) | Volume at 10 cm H2O (mL) | Volume at 20 cm H2O (mL) | Volume at 35 cm H2O (mL) |
---|---|---|---|---|---|---|
Ctr | 0.16 ± 0.02 | 0.38 ± 0.03 | 0.72 ± 0.04* | 1.03 ± 0.06* | 1.22 ± 0.06* | 1.32 ± 0.06* |
Neo CS | 0.14 ± 0.01 | 0.42 ± 0.02 | 0.84 ± 0.02 | 1.19 ± 0.03 | 1.37 ± 0.03** | 1.48 ± 0.03** |
Adult CS | 0.23 ± 0.04 | 0.51 ± 0.04† | 0.92 ± 0.05† | 1.32 ± 0.07† | 1.60 ± 0.08† | 1.72 ± 0.09† |
Neo CS + Adult CS | 0.20 ± 0.03 | 0.62 ± 0.07‡ | 1.03 ± 0.07‡ | 1.46 ± 0.07‡ | 1.76 ± 0.08‡ | 1.88 ± 0.08‡ |
Note. Quasistatic pressure-volume curves were performed and volumes (mL) were measured at −10, 0, 5, 10, 20, and 35 cm H2O (± SEM). n = 5–8 per group.
Ctr had significantly lower volumes at 5, 10, 20, and 35 cm H2O compared to Neo CS (P < .04).
Neo CS had significantly lower volumes at 20 and 35 cm H2O compared to Adult CS (P < .03).
Adult CS had significantly higher volumes at 0–35 cm H2O compared to Ctr (P < .04).
Neo CS + Adult CS had significantly higher volumes at 0 to 35 cm H2O compared to both Ctr and Neo CS (P < .01).