Table 3.

Determinants of Choice of Therapy: Clinical Factors

Factor	LR v LT		LR v RFA		RFA v LT		P
	RRR	95% CI	RRR	95% CI	RRR	95% CI
Age, years
50	Ref		Ref		Ref		.046
65	1.11	0.96 to 1.29	0.78	0.57 to 1.05	1.44	1.06 to 1.95
Tumor number and size
3 tumors; largest, 2.5 cm	Ref		Ref		Ref		< .001
1 tumor; 4.5 cm	1.72	1.35 to 2.19	3.23	1.57 to 6.64	0.53	0.26 to 1.07
1 tumor; 2.5 cm	2.27	1.76 to 2.93	0.40	0.24 to 0.68	5.65	3.48 to 9.16
Type of resection required
Left hemi-hepatectomy, FLR 60%	Ref		Ref		Ref		< .001
Right posterior section, FLR 70%	1.54	1.23 to 1.94	1.34	0.89 to 2.02	1.15	0.80 to 1.65
Left lateral section, FLR 85%	4.19	3.31 to 5.31	5.79	3.61 to 9.30	0.72	0.47 to 1.12
Etiology of cirrhosis*
Chronic hepatitis C	Ref		Ref		Ref		< .001
Chronic hepatitis B	1.18	0.95 to 1.47	0.75	0.50 to 1.12	1.58	1.08 to 2.32
Past alcohol abuse	1.47	1.21 to 1.80	1.08	0.74 to 1.59	1.36	0.94 to 1.97
Biologic MELD score
10	Ref		Ref		Ref		< .001
8	1.44	1.18 to 1.77	1.46	0.94 to 2.28	0.99	0.65 to 1.49
6	1.66	1.37 to 2.02	1.56	1.03 to 2.37	1.06	0.71 to 1.59
Platelet count, per μL
90,000	Ref		Ref		Ref		< .001
150,000	2.32	1.93 to 2.79	1.97	1.43 to 2.73	1.18	0.87 to 1.59
Liver transplantation waiting time, months
2	Ref		Ref		Ref		< .001
5	1.30	1.08 to 1.57	0.98	0.60 to 1.60	1.33	0.83 to 2.11
8	1.70	1.39 to 2.09	1.20	0.77 to 1.88	1.41	0.93 to 2.15

Abbreviations: LR, liver resection; LT, liver transplantation; RFA, radiofrequency ablation; RRR, relative risk ratio; Ref, referent; FLR, future liver remnant; MELD, model for end-stage liver disease.

^*All patients were described as having Child's A cirrhosis.