Table A1.

Determinants of Choice of Therapy, Including Surgeon Specialty

Factor	LR v LT		LR v RFA		RFA v LT		P
	RRR	95% CI	RRR	95% CI	RRR	95% CI
Age, years
50	Ref		Ref		Ref		.064
65	1.10	0.95 to 1.28	0.77	0.57 to 1.05	1.43	1.05 to 1.95
Tumor number and size
3 tumors; largest, 2.5 cm	Ref		Ref		Ref		< .001
1 tumor; 4.5 cm	1.81	1.41 to 2.32	3.26	1.58 to 6.74	0.55	0.27 to 1.12
1 tumor; 2.5 cm	2.46	1.89 to 3.20	0.40	0.24 to 0.68	6.11	3.71 to 10.1
Type of resection required
Left hemi-hepatectomy, FLR 60%	Ref		Ref		Ref		< .001
Right posterior section, FLR 70%	1.56	1.23 to 1.97	1.34	0.89 to 2.01	1.17	0.82 to 1.67
Left lateral section, FLR 85%	4.44	3.49 to 5.64	5.85	3.64 to 9.41	0.76	0.49 to 1.18
Etiology of cirrhosis*
Chronic hepatitis C	Ref		Ref		Ref		< .001
Chronic hepatitis B	1.18	0.94 to 1.48	0.75	0.50 to 1.11	1.59	1.08 to 2.33
Past alcohol abuse	1.51	1.23 to 1.85	1.08	0.74 to 1.58	1.40	0.97 to 2.02
Biologic MELD score
10	Ref		Ref		Ref		< .001
8	1.41	1.15 to 1.74	1.44	0.92 to 2.24	0.98	0.65 to 1.49
6	1.68	1.37 to 2.04	1.56	1.03 to 2.37	1.07	0.71 to 1.61
Platelet count, per μL
90,000	Ref		Ref		Ref		< .001
150,000	2.36	1.96 to 2.85	2.00	1.45 to 2.77	1.18	0.87 to 1.60
Liver transplantation waiting time, months
2	Ref		Ref		Ref		< .001
5	1.34	1.10 to 1.64	0.99	0.61 to 1.60	1.36	0.85 to 2.18
8	1.73	1.39 to 2.14	1.20	0.77 to 1.88	1.44	0.94 to 2.20
Liver transplantation surgeon
Yes	Ref		Ref		Ref		< .001
No	2.67	2.00 to 3.55	1.01	0.63 to 1.62	2.64	1.62 to 4.30

Abbreviations: LR, liver resection; LT, liver transplantation; RFA, radiofrequency ablation; RRR, relative risk ratio; Ref, referent; FLR, future liver remnant; MELD, model of end-stage liver disease.

^*All patients were described as having Child's A cirrhosis.