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. Author manuscript; available in PMC: 2016 Apr 18.
Published in final edited form as: Ann Surg Oncol. 2014 Oct 30;22(7):2218–2225. doi: 10.1245/s10434-014-4223-3

TABLE 3.

Significant prognostic factors for overall survival of group B patients

Univariable analysis Multivariable analysis


HR 95 % CI P value HR 95 % CI P value
Age >60 years 1.06 (0.82–1.38) 0.63
Male gender 1.07 (0.83–1.39) 0.59
No. of lesions >3 1.7 (1.22–2.37) <0.001 1.56 (1.09–2.23) 0.02
Cirrhosis 1.24 (0.79–1.95) 0.34
Vascular invasion 1.31 (1.00–1.72) 0.05
Perineural invasion 0.88 (0.61–1.27) 0.49
Biliary invasion 1.41 (0.99–2.01) 0.05
Direct invasion of contiguous organs 1.39 (0.95–2.03) 0.09
Nodal metastasis 1.71 (1.25–2.34) <0.001 1.47 (1.05–2.07) 0.02
Poor tumor differentiation 1.53 (1.16–2.02) <0.001 1.48 (1.11–1.96) 0.01
Major hepatectomy 1.05 (0.79–1.41) 0.73
R1 margins 1.29 (0.90–1.85) 0.16
No. lymphadenectomy 1.07 (0.83–1.39) 0.60
No. of lymph node harvested <3 0.85 (0.60–1.21) 0.36

HR hazard ratio, CI confidence interval.