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. 2014 Apr 30;6(3):e00142. doi: 10.1042/AN20130031

Figure 3. GO-annotations of differentially expressed genes due to forskolin treatment.

Figure 3

Analysis of molecular functions revealed that several transcripts increased with forskolin are associated with cytoskeletal protein and actin binding. Both sets of transcripts either increased or decreased due to forskolin manifested association with the cellular component of ECM and with the plasma membrane. The term of basement membrane and integrin complex was exclusively enriched in forskolin-reduced transcripts. GO-annotation analysis of transcripts decreased with forskolin showed an enrichment of genes implicated in intracellular signaling cascade and in the MAPKK cascade. Raw data are provided as Supplementary Table S4 (available at http://www.asnneuro.org/an/006/an006e142add.htm).