Figure 4. Effect of forskolin treatment on mRNA expression levels of known components of the ECM in Schwann cells.
(A) Data analysis of the microarray was performed by a two-way ANOVA, and unadjusted P-values <0.01 were accounted as significant. Forskolin had a regulatory effect on the majority of investigated ECM-associated genes. n.s.: not significant. (B) Schematic illustration of components of the ECM and the basal lamina in Schwann cells. The effect of forskolin on gene expression of selected genes associated with the ECM and the basal lamina (red line) was shown by blue (reduced), red (increased) or green (unaltered) arrows.